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Acceptability and tolerability of repeated intramuscular electroporation of Multi-antigenic HIV (HIVMAG) DNA vaccine among healthy African participants in a phase 1 randomized controlled trial.

<h4>Introduction</h4>Intramuscular electroporation (IM/EP) is a vaccine delivery technique that improves the immunogenicity of DNA vaccines. We evaluated the acceptability and tolerability of electroporation among healthy African study participants.<h4>Methods</h4>Forty-five participants were admini...

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Principais autores: Juliet Mpendo, Gaudensia Mutua, Annet Nanvubya, Omu Anzala, Julien Nyombayire, Etienne Karita, Len Dally, Drew Hannaman, Matt Price, Patricia E Fast, Frances Priddy, Huub C Gelderblom, Nancy K Hills
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2020-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0233151
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