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Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes: a proof of concept

The production of clinically relevant quantities of human mesenchymal stromal cells (hMSCs) requires scalable and intensified manufacturing processes. For this reason, the applicability of alternating tangential flow filtration (ATF) and tangential flow depth filtration (TFDF) based cell retention s...

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Autori principali: Samuel Lukas Schneider, Abiram Gopalakrishnan, Misha Alexander Teale, Regine Eibl
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-07-01
Serie:Frontiers in Bioengineering and Biotechnology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1611703/full
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