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Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

<p>Abstract</p> <p>Background</p> <p>In eukaryotes, RNA interference (RNAi) is a major mechanism of defense against viruses and transposable elements as well of regulating translation of endogenous mRNAs. The RNAi systems recognize the target RNA molecules via small guide RNAs that are completely or...

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Principais autores: van der Oost John, Wolf Yuri I, Makarova Kira S, Koonin Eugene V
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2009-08-01
Colecção:Biology Direct
Acesso em linha:http://www.biology-direct.com/content/4/1/29
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