Development of synergistic antifungal in situ gel of miconazole nitrate loaded microemulsion as a novel approach to treat vaginal candidiasis

Abstract Limited solubility is the main cause of the low local availability of anti-candidiasis drug, miconazole nitrate (MN). The study’s objective was to develop and characterize microemulsion (ME) based temperature-triggered in situ gel of MN for intravaginal administration to enhance local avail...

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Egile Nagusiak:	Omar M. Alwan, Iman S. Jaafar
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2024-10-01
Saila:	Scientific Reports
Gaiak:	Miconazole nitrate Microemulsion Essential oil Antifungal action Solubility enhancement In situ gel
Sarrera elektronikoa:	https://doi.org/10.1038/s41598-024-74021-3
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