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Inhibitors targeting the autophosphorylation of serine/threonine kinase of Streptococcus suis show potent antimicrobial activity

Antimicrobial resistance (AMR) is a global concern threatening public health. Developing novel antibiotics is one of the effective strategies to tackle AMR. Serine/threonine kinases (STKs) have been recently shown to play critical roles in the physiology and pathogenesis of several important bacteri...

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Principais autores: Haotian Li, Tingting Li, Qiao Hu, Zhiming Yao, Lu Li, Qi Huang, Rui Zhou
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-09-01
Serier:Frontiers in Microbiology
Fag:
serine/threonine kinase
antimicrobial
drug target
autophosphorylation
inhibitor
Streptococcus suis
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2022.990091/full
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