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The subcellular distribution of miRNA isoforms, tRNA-derived fragments, and rRNA-derived fragments depends on nucleotide sequence and cell type

Abstract Background MicroRNA isoforms (isomiRs), tRNA-derived fragments (tRFs), and rRNA-derived fragments (rRFs) represent most of the small non-coding RNAs (sncRNAs) found in cells. Members of these three classes modulate messenger RNA (mRNA) and protein abundance and are dysregulated in diseases....

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Principais autores: Tess Cherlin, Yi Jing, Siddhartha Shah, Anne Kennedy, Aristeidis G. Telonis, Venetia Pliatsika, Haley Wilson, Lily Thompson, Panagiotis I. Vlantis, Phillipe Loher, Benjamin Leiby, Isidore Rigoutsos
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-09-01
Series:BMC Biology
Assuntos:
Small non-coding RNAs
sncRNAs
microRNAs
miRNAs
miRNA isoforms
isomiRs
Acceso en liña:https://doi.org/10.1186/s12915-024-01970-6
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