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Reassortment and mutations associated with emergence and spread of oseltamivir-resistant seasonal influenza A/H1N1 viruses in 2005-2009.

A dramatic increase in the frequency of the H275Y mutation in the neuraminidase (NA), conferring resistance to oseltamivir, has been detected in human seasonal influenza A/H1N1 viruses since the influenza season of 2007-2008. The resistant viruses emerged in the ratio of 14.3% and quickly reached 10...

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Detalles Bibliográficos
Principais autores: Ji-Rong Yang, Yu-Cheng Lin, Yuan-Pin Huang, Chun-Hui Su, Je Lo, Yu-Lin Ho, Ching-Yuan Yao, Li-Ching Hsu, Ho-Sheng Wu, Ming-Tsan Liu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3069057?pdf=render
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