Engineering of Corynebacterium glutamicum for biosynthesis of the pharmaceutically active N-acetyltyramine: establishing and optimizing de novo production

Abstract Background N-Acetyltyramine is increasingly recognized for its diverse pharmaceutically relevant properties. In particular, it exhibits antimicrobial activity against multi-drug resistant pathogens, which pose a considerable health challenge. Therefore, the demand for a sustainable and effi...

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Auteurs principaux:	Sara-Sophie Poethe, Lilli Sophie Kaimann, Kai H. Schülke, Stephan C. Hammer, Volker F. Wendisch
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-06-01
Collection:	Journal of Biological Engineering
Sujets:	Corynebacterium glutamicum N-Acetyltyramine N-Propionyltyramine Arylalkylamine N-acetyltransferase Design of experiments
Accès en ligne:	https://doi.org/10.1186/s13036-026-00713-1
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