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Histone H3 Lysine 56 Acetylation Is Required for Formation of Normal Levels of Meiotic DNA Breaks in S. cerevisiae

Meiotic recombination is initiated by Spo11-catalyzed DNA double-strand breaks (DSBs) that are promoted by histone modifications and histone modifying enzymes. Herein we investigated the role of histone H3 lysine 56 acetylation (H3K56ac) located near the entry/exit points of the DNA in the globular...

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Principais autores: Zsolt Karányi, Lilla Hornyák, Lóránt Székvölgyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-01-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
recombination
DNA break
meiosis
histone modification
H3K56 acetylation
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcell.2019.00364/full
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