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Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB

BackgroundTo generate an ancestry-resolved pharmacogenomic (PGx) landscape for Colombia by integrating all PharmGKB variant-drug annotations with local allele-frequency data, thereby quantifying inter-ancestry differences of clinical relevance and exposing evidence gaps that hinder equitable precisi...

Täydet tiedot

Tallennettuna:
Päätekijät: Andy A. Acosta-Monterrosa, Kevin Fernando Montoya-Quintero, Johana Galván-Barrios, Indiana Luz Rojas Torres
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2025-08-01
Sarja:Frontiers in Pharmacology
Aiheet:
pharmacogenomic variants
precision medicine
pharmacogenetics
genomics
Colombia
Linkit:https://www.frontiersin.org/articles/10.3389/fphar.2025.1636451/full
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