Novel Concepts of Altered Immunoglobulin G Galactosylation in Autoimmune Diseases
The composition of the conserved N297 glycan in immunoglobulin G (IgG) has been shown to affect antibody effector functions via C1q of the complement system and Fc gamma receptors (FcγR) on immune cells. Changes in the general levels of IgG-glycoforms, such as lowered total IgG galactosylation obser...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018-03-01
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| Serie: | Frontiers in Immunology |
| Soggetti: | |
| Accesso online: | http://journal.frontiersin.org/article/10.3389/fimmu.2018.00553/full |
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