Transcriptome exploration of ferroptosis-related genes in TGFβ- induced lens epithelial to mesenchymal transition during posterior capsular opacification development

Abstract Background Posterior capsular opacification (PCO) is the main reason affecting the long-term postoperative result of cataract patient, and it is well accepted that fibrotic PCO is driven by transforming growth factor beta (TGFβ) signaling. Ferroptosis, closely related to various ocular dise...

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Hlavní autoři:	Cong Fan, Chao Wang, Yan Wang, Jian Jiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-04-01
Edice:	BMC Genomics
Témata:	RNA-sequencing Transforming growth factor beta Primary lens epithelial cells Posterior capsular opacification Epithelial-mesenchymal transition
On-line přístup:	https://doi.org/10.1186/s12864-024-10244-y
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