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E2F transcription factors as multimodal biomarkers for pan-cancer management

Abstract Early 2 factor (E2F) genes are transcription factors that interact with many DNAs and proteins. Studies have demonstrated that E2F genes can play an oncogenic role in different cancers, yet fewer have explored their effects on pan-cancers. In this study, E2F expression is systematically cha...

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Principais autores: Shaobo Yang, Kai Li, Yong Suo, Zhe Zhang, Houyuan Chen, Yuda Lin, Chong Fu, Yunkai Qie, Chong Shen, Hailong Hu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-12-01
סדרה:Scientific Reports
נושאים:
Pan-cancer
E2F family
Prognosis
Immunotherapy response
Multi-omics
גישה מקוונת:https://doi.org/10.1038/s41598-025-31042-w
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