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SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy

Many recent studies have demonstrated the involvement of endoplasmic reticulum (ER) stress in the development of cardiac diseases and have suggested that modulation of ER stress response could be cardioprotective. Previously, we demonstrated that the deacetylase Sirtuin 1 (SIRT1) attenuates ER stres...

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Kaydedildi:
Asıl Yazarlar: Julie Pires Da Silva, Kevin Monceaux, Arnaud Guilbert, Mélanie Gressette, Jérôme Piquereau, Marta Novotova, Renée Ventura-Clapier, Anne Garnier, Christophe Lemaire
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-02-01
Seri Bilgileri:Cells
Konular:
sirtuin 1
endoplasmic reticulum stress
autophagy/mitophagy
cell death
cardioprotection
Online Erişim:https://www.mdpi.com/2073-4409/9/2/426
Etiketler: Etiketle
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