The distribution and 'in vivo' phase variation status of haemoglobin receptors in invasive meningococcal serogroup B disease: genotypic and phenotypic analysis.

Two haemoglobin-binding proteins, HmbR and HpuAB, contribute to iron acquisition by Neisseria meningitidis. These receptors are subject to high frequency, reversible switches in gene expression--phase variation (PV)--due to mutations in homopolymeric (poly-G) repeats present in the open reading fram...

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Autori principali:	Jay Lucidarme, Jamie Findlow, Hannah Chan, Ian M Feavers, Stephen J Gray, Edward B Kaczmarski, Julian Parkhill, Xilian Bai, Ray Borrow, Christopher D Bayliss
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2013-01-01
Serie:	PLoS ONE
Accesso online:	https://doi.org/10.1371/journal.pone.0076932
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