Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes

Abstract Background Altered neuronal connectivity in peri-infarct tissue is an important contributor to both the spontaneous recovery of neurological function that commonly develops after stroke and improvements in recovery that have been induced by experimental treatments in animal models. Microgli...

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Hlavní autoři:	Wai Ping Yew, Natalia D. Djukic, Jaya S. P. Jayaseelan, Frederick R. Walker, Karl A. A. Roos, Timothy K. Chataway, Hakan Muyderman, Neil R. Sims
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-01-01
Edice:	Journal of Neuroinflammation
Témata:	Stroke Focal ischemia Microglia Astrocytes Minocycline Functional recovery
On-line přístup:	http://link.springer.com/article/10.1186/s12974-018-1379-y
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