Cellular Crosstalk Promotes Hepatic Progenitor Cell Proliferation and Stellate Cell Activation in 3D Co-cultureSummary

Background & Aims: Following liver damage, ductular reaction often coincides with liver fibrosis. Proliferation of hepatic progenitor cells is observed in ductular reaction, whereas activated hepatic stellate cells (HSCs) are the main drivers of liver fibrosis. These observations may suggest a f...

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Autori principali:	Maya W. Haaker, Jung-Chin Chang, Brian K. Chung, Tobias S. Pieper, Falko Noé, Tongtong Wang, Niels Geijsen, Martin Houweling, Christian Wolfrum, Arie B. Vaandrager, Espen Melum, Bart Spee, J. Bernd Helms
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-01-01
Serie:	Cellular and Molecular Gastroenterology and Hepatology
Soggetti:	Ductular Reaction Intrahepatic Cholangiocyte Organoid Liver Fibrosis Retinoic Acid
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2352345X2500013X
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