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Bioinspired Antimicrobial Strategy: An Extremophile Deep Sea Peptide to Combat Cystic Fibrosis Infections Caused by <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i>

Cystic fibrosis (CF)-associated lung infections caused by <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) and <i>Staphylococcus aureus</i> (<i>S. aureus</i>) remain difficult to treat due to multidrug resistance and the redox instability of the pulmonary environment, which can impair antibiotic...

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Main Authors: Céline Boidin-Wichlacz, Marc Maresca, Teddy Grandjean, Axelle Grandé, Orane Huchez, Katy Jeannot, Rémi Desmet, Benoît Snella, Nicolas Vidal, Laure Genet, Stéphanie Caby, Magalie Sénéchal, Sophie Guillier, Fabienne Ripoll-Neulat, Oleg Melnyk, Muriel Pichavant, Aurélie Tasiemski
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-05-01
Series:Marine Drugs
Subjects:
antibiotic
resistance
antibiofilm
extremophile
worms
biomimicry
Online Access:https://www.mdpi.com/1660-3397/24/5/164
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