Management of hematological toxicities after BCMA-directed CAR-T cell therapy

Abstract The CAR-HEMATOTOX (CAR-HT) score can assess hematotoxicity risk, but its utility in guiding supportive care remains underexplored. We analyzed 224 multiple myeloma patients treated with BCMA-directed CAR-T therapy (2016–2024), stratified by CAR-HT score (low <2 vs high ≥2). We evaluated the...

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Bibliografiske detaljer

Principais autores:	Joselle Cook, Supriya Gupta, Nadine Abdallah, Matthew Rees, Christopher Graham, Lay She Ng, Radhika Bansal, Andre De Menezes Silva Corraes, Kristina Helms, Rahma Warsame, David Dingli, Wilson Gonsalves, Taxiarchis Kourelis, Morie Gertz, Suzanne Hayman, Nelson Leung, Prashant Kapoor, Lisa Hwa, Amie Fonder, Miriam Hobbs, Leif Bergsagel, Udit Yadav, Erin Wiedmeier-Nutor, Saurabh Chhabra, Rafael Fonseca, Sikander Ailawadhi, Ricardo Parrondo, Shaji Kumar, Yi Lin
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2026-03-01
Serier:	Blood Cancer Journal
Online adgang:	https://doi.org/10.1038/s41408-026-01455-5
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