Fluorescence-based bioassay for the detection of changes in mitochondrial physiology during artemisinin-induced growth arrest of blood-stage Plasmodium falciparum

Abstract The emergence of artemisinin (ART) resistance in Plasmodium falciparum challenges global malaria treatment programs. To avoid ART-induced death, a proportion of ring-stage parasites arrest and resume cyclic intraerythrocytic growth, leading to recrudescent malaria. However, the direct track...

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Detalhes bibliográficos

Principais autores:	Narisara Whangviboonkij, Kasem Kulkeaw, Mallika Imwong, Porntida Kobpornchai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-12-01
coleção:	Scientific Reports
Assuntos:	Plasmodium falciparum Growth-arrested parasite Mitochondria-based fluorochromes Artemisinin resistance Recrudescence
Acesso em linha:	https://doi.org/10.1038/s41598-025-29777-7
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