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The lifespan and healthspan extending effects of ellagic acid in Caenorhabditis elegans require an intact insulin/IGF-1 signaling pathway

IntroductionEllagic acid (EA) is a naturally occurring polyphenolic antioxidant speculated to influence aging, but its precise biological mechanisms remain poorly understood.MethodsUsing Caenorhabditis elegans as a model system, we investigated the anti-aging properties of EA. Lifespan assays were p...

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Principais autores: Lipeng Xu, Jinze Li, Anran Li, Jixian Chen, Liping Wang, Yaming Shan, Xianbin Cheng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-05-01
Series:Frontiers in Aging
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fragi.2026.1811330/full
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