Neoadjuvant sintilimab, albumin-bound paclitaxel, and carboplatin for locally advanced, resectable esophageal squamous cell carcinoma: clinical study and mechanistic exploration

Abstract The survival benefits of neoadjuvant chemotherapy combined with immunotherapy in locally advanced esophageal squamous cell carcinoma (ESCC) remain unclear, with treatment responses varying due to tumor microenvironment (TME) heterogeneity. In this phase II study, 24 patients received neoadj...

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Autors principals:	Hui Wu, Qi Jiang, Xiaodan Li, Peng Ye, Aizemaiti Rusidanmu, Ning Li, Xiaodong Teng, Qiyue Wang, Yinqi Chen, Dongdong Huang, Yuejun Han, Bingnan Wang, Wenhong Yu, Jian Tao, Jian Ruan, Haiping Jiang
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-01-01
Col·lecció:	npj Precision Oncology
Accés en línia:	https://doi.org/10.1038/s41698-025-01248-2
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