RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1.
The human cytidine deaminase APOBEC3G (A3G) is a potent inhibitor of retroviruses and transposable elements and is able to deaminate cytidines to uridines in single-stranded DNA replication intermediates. A3G contains two canonical cytidine deaminase domains (CDAs), of which only the C-terminal one...
Shranjeno v:
| Principais autores: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2009-03-01
|
| Serija: | PLoS Pathogens |
| Online dostop: | https://doi.org/10.1371/journal.ppat.1000330 |
| Oznake: |
Brez oznak, prvi označite!
|