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Mechanisms controlling the trafficking, localization, and abundance of presynaptic Ca2+ channels

Voltage-gated Ca2+ channels (VGCCs) mediate Ca2+ influx to trigger neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The abundance of VGCCs at AZs regulates neurotransmitter release probability (Pr), a key presynaptic determinant of synaptic strength. Given this fu...

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Váldodahkkit: Karen L. Cunningham, J. Troy Littleton
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2023-01-01
Ráidu:Frontiers in Molecular Neuroscience
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1116729/full
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