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Mechanozyme: An Artificial Enzyme With a Mechanophore Framework

ABSTRACT Conformational flexibility of natural enzymes, characterized by marginal stability, displays functional variations. In this work, we uncovered that artificial DNAzymes made of G‐quadruplex (GQ)‐hemin complexes also display this marginal stability phenomenon. Through single‐molecule fluoresc...

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Principais autores: Jiahao Ji, Pravin Pokhrel, Sajan Shakya, Bishal Pokhrel, Grinsun Sharma, Pratiksha Chaudhary, Hao Shen, Hanbin Mao
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-07-01
Serier:Advanced Science
Fag:
DNAzyme
marginal stability
mechanical modulation
mechanochemistry
ultrasonication
Online adgang:https://doi.org/10.1002/advs.75254
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