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Genomic Signatures of Immune Activation Predict Outcome in Advanced Stages of Ovarian Cancer and Basal-Like Breast Tumors

There is an unmet need for new therapies in metastatic ovarian cancer and basal-like breast cancer since no curative therapies are currently available. Immunotherapy has shown to be active in several solid tumors, but particularly more in those where a pre-activated immune state does exist. In this...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ana Alcaraz-Sanabria, Mariona Baliu-Piqué, Cristina Saiz-Ladera, Katerin Rojas, Aránzazu Manzano, Gloria Marquina, Antonio Casado, Francisco J. Cimas, Pedro Pérez-Segura, Atanasio Pandiella, Balázs Gyorffy, Alberto Ocana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-01-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
ovarian cancer
breast cancer
genomic signatures
immune infiltrates
biomarkers
Online-Zugang:https://www.frontiersin.org/article/10.3389/fonc.2019.01486/full
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