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Differential spatial distribution of HNF4α isoforms during dysplastic progression of intraductal papillary mucinous neoplasms of the pancreas

Abstract Hepatocyte Nuclear Factor 4-alpha (HNF4α) comprises a nuclear receptor superfamily of ligand-dependent transcription factors that yields twelve isoforms in humans, classified into promoters P1 or P2-associated groups with specific functions. Alterations in HNF4α isoforms have been associate...

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Autors principals: Jahg Wong, Vincent Q. Trinh, Nidhi Jyotsana, Jumanah F. Baig, Frank Revetta, Chanjuan Shi, Anna L. Means, Kathleen E. DelGiorno, Marcus Tan
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2023-11-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-023-47238-x
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