Exercise-conditioned plasma ameliorates postoperative cognitive dysfunction by activating hippocampal cholinergic circuit and enhancing BDNF/TrkB signaling

Abstract Background Postoperative cognitive dysfunction (POCD) is a prevalent complication following anesthesia and surgery, particularly in the elderly, leading to increased mortality and reduced quality of life. Despite its prevalence, there are no effective clinical treatments. Exercise has shown...

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Ngā kaituhi matua:	Xiaodi Lu, Weijie Xiong, Zhuo Chen, Yurou Li, Fengyan Xu, Xue Yang, Meiwen Long, Wenhan Guo, Shuliang Wu, Liang Sun, Guonian Wang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2024-11-01
Rangatū:	Cell Communication and Signaling
Ngā marau:	POCD Exercise Plasma Cholinergic circuit BDNF/TrkB
Urunga tuihono:	https://doi.org/10.1186/s12964-024-01938-7
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!