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Detection of sputum cofilin-1 as indicator of malignancy

Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an indicator of malignancy and aggressiveness in sputum samples. CFL1 was analyzed by ELISA immunoassay in the sputum of 73 lung c...

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Wedi'i Gadw mewn:
Prif Awduron: M.P. Rangel, L. Antonangelo, M.M.P. Acencio, C.S. Faria, V.K. de Sá, P.S. Leão, C. Farhat, A.T. Fabro, A. Longatto Filho, R.M. Reis, T. Takagaki, V.L. Capelozzi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Associação Brasileira de Divulgação Científica 2018-05-01
Cyfres:Brazilian Journal of Medical and Biological Research
Pynciau:
Lung cancer
Cofilin-1
Sputum
Liquid-biopsy
Metastases
Biomarker
Mynediad Ar-lein:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800603&lng=en&tlng=en
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