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BMSC-derived exosomal miR-27a-3p and miR-196b-5p regulate bone remodeling in ovariectomized rats

Background In the bone marrow microenvironment of postmenopausal osteoporosis (PMOP), bone marrow mesenchymal stem cell (BMSC)-derived exosomal miRNAs play an important role in bone formation and bone resorption, although the pathogenesis has yet to be clarified. Methods BMSC-derived exosomes from o...

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Autors principals: Guohua Lai, Renli Zhao, Weida Zhuang, Zuoxu Hou, Zefeng Yang, Peipei He, Jiachang Wu, Hongxun Sang
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2022-09-01
Col·lecció:PeerJ
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Accés en línia:https://peerj.com/articles/13744.pdf
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