Halogenation generates effective modulators of amyloid-Beta aggregation and neurotoxicity.

Halogenation of organic compounds plays diverse roles in biochemistry, including selective chemical modification of proteins and improved oral absorption/blood-brain barrier permeability of drug candidates. Moreover, halogenation of aromatic molecules greatly affects aromatic interaction-mediated se...

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Hlavní autoři:	H Edward Wong, Jacob A Irwin, Inchan Kwon
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2013-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC3585355?pdf=render
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