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Genome-wide association studies of missing metabolite measures from two population-based studies

Abstract Background Metabolomic analyses are increasingly applied in both etiological and predictive research, but frequently report missing values, which are then either imputed or removed from the analyses, and not examined as true missingness due to altered metabolism. We hypothesized that interi...

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I tiakina i:
Ngā kaituhi matua: Tariq O. Faquih, Mohammed Aslam Imtiaz, Valentina Talevi, Elvire N. Landstra, Astrid van Hylckama Vlieg, Ruifang Li-Gao, Frits R. Rosendaal, Raymond Noordam, Diana van Heemst, Dennis O. Mook-Kanamori, Monique M. B. Breteler, N. Ahmad Aziz, Ko Willems van Dijk
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-07-01
Rangatū:Genome Biology
Ngā marau:
Genome-wide association study
Missing measurements
Inborn errors of metabolism
Metabolomics
Poor metabolizers
Urunga tuihono:https://doi.org/10.1186/s13059-026-04132-9
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