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Structure and dynamics underlying elementary ligand binding events in human pacemaking channels

Although molecular recognition is crucial for cellular signaling, mechanistic studies have relied primarily on ensemble measures that average over and thereby obscure underlying steps. Single-molecule observations that resolve these steps are lacking due to diffraction-limited resolution of single f...

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Detalhes bibliográficos
Principais autores: Marcel P Goldschen-Ohm, Vadim A Klenchin, David S White, John B Cowgill, Qiang Cui, Randall H Goldsmith, Baron Chanda
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2016-11-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/20797
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