In silico studies, X-ray diffraction analysis and biological investigation of fluorinated pyrrolylated-chalcones in zebrafish epilepsy models

Epilepsy is the third most common known brain disease worldwide. Several antiepileptic drugs (AEDs) are available to improve seizure control. However, the associated side effects limit their practical use and highlight the ongoing search for safer and effective AEDs. Eighteen newly designed fluorine...

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Auteurs principaux:	Muhammad Syafiq Akmal Mohd Fahmi, Puspanjali Swain, Amirah Hani Ramli, Wan Norhamidah Wan Ibrahim, Nur Atikah Saleh Hodin, Noraini Abu Bakar, Yee Seng Tan, Siti Munirah Mohd Faudzi, Cheol-Hee Kim
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2023-02-01
Collection:	Heliyon
Sujets:	Chalcones Antiepileptic drugs (AEDs) Zebrafish
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2405844023008927
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