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Novel Pyrrole-Based Hydrazide–Hydrazones: Synthesis, In Vitro Evaluation of Antioxidant and Neuroprotective Activity, In Silico ADME, and DFT Studies

Pyrrole-based hydrazide–hydrazones constitute a class of organic compounds that has attracted increasing attention in pharmaceutical research due to their potential application in the treatment of neurodegenerative diseases. In the present study, a series of ten novel pyrrole-containing hydrazide–hy...

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Principais autores: Valentin Karatchobanov, Emilio Mateev, Iva Valkova, Magdalena Kondeva-Burdina, Maya Georgieva
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-05-01
Serier:Antioxidants
Fag:
pyrrole
hydrazide–hydrazone
antioxidants
oxidative stress
neuroprotection
ADME
Online adgang:https://www.mdpi.com/2076-3921/15/6/666
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