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Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy

Leprosy is a spectral disease exhibiting two polar sides, namely, lepromatous leprosy (LL) characterised by impaired T-cell responses and tuberculoid leprosy in which T-cell responses are strong. Proper T-cell activation requires signalling through costimulatory molecules expressed by antigen presen...

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Principais autores: Maria de Lourdes Palermo, Maria Ângela Bianconcini Trindade, Alberto José da Silva Duarte, Camila Rodrigues Cacere, Gil Benard
Formato: Artigo
Idioma:Inglês
Publicado: Fundação Oswaldo Cruz (FIOCRUZ) 2012-12-01
Series:Memorias do Instituto Oswaldo Cruz
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Acceso en liña:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000900024&lng=en&tlng=en
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