Activated protein C ameliorates diabetes-induced atherosclerosis by sustaining macrophage efferocytosis

Abstract Macrophage efferocytosis, essential for the resolution of inflammation and plaque stability in atherosclerosis, is impaired in diabetes. Thrombomodulin (TM) and endothelial protein C receptor (EPCR), key mediators of protein C activation (PC), have vasculoprotective and anti-inflammatory ro...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Saira Ambreen, Amna Arif, Saikal Shamkeeva, Ahmed Elwakiel, Surinder Pal, Shihai Jiang, Muhammad Asad Farhan, Zuhir Halloul, John H. Griffin, Berend Isermann, Khurrum Shahzad
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2025-10-01
סדרה:	Cardiovascular Diabetology
נושאים:	Atherosclerosis Diabetes Macrophage Efferocytosis Protein C
גישה מקוונת:	https://doi.org/10.1186/s12933-025-02965-5
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!