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Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro‐β‐erythroidine in nicotine‐tolerant mice

Abstract Objectives There is a long‐standing interest in developing nicotinic acetylcholine receptor (nAChR) antagonists for concomitant use with nAChR agonists (e.g., nicotine replacement) as complementary smoking cessation aids. Previous studies demonstrate that daily nicotine treatment confers to...

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Bibliografske podrobnosti
Principais autores: Fernando B. deMoura, Jenny L. Wilkerson, Lance R. McMahon
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2020-04-01
Serija:Brain and Behavior
Teme:
Online dostop:https://doi.org/10.1002/brb3.1581
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