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Anticancer Activity of <i>Jania rubens</i> in HCT-116 Cells via EMT Suppression, TET Downregulation, and ROS-Mediated Cytotoxicity

The red seaweed <i>Jania rubens</i> (<i>J. rubens</i>) is prevalent along the Lebanese coast and has drawn attention for its notable antineoplastic properties. Our previous data showed that its dichloromethane–methanol (DM) extract possesses antioxidant, cytotoxic, and anti-migratory effects on colo...

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Principais autores: Zeina Radwan, Rayan Kassir, Fouad Al Feghaly, Rouaa Zaiter, Mira Abou Daher, Rabih Roufayel, Ziad Fajloun, Hiba Mawlawi, Marwan El-Sabban, Zeina Dassouki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-09-01
coleção:Biomolecules
Assuntos:
<i>Jania rubens</i>
colorectal cancer
anticancer activity
epithelial-to-mesenchymal transition (EMT)
TET enzymes
reactive oxygen species (ROS)
Acesso em linha:https://www.mdpi.com/2218-273X/15/10/1361
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