First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

Abstract Background Efforts to develop suitable positron emission tomography (PET) tracers for the ion channel site of human N-methyl-d-aspartate (NMDA) receptors have had limited success. [18F]PK-209 is a GMOM derivative that binds to the intrachannel phencyclidine site with high affinity and selec...

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Detalhes bibliográficos

Principais autores:	Jasper van der Aart, Sandeep S. V. Golla, Marieke van der Pluijm, Lothar A. Schwarte, Robert C. Schuit, Pieter J. Klein, Athanasios Metaxas, Albert D. Windhorst, Ronald Boellaard, Adriaan A. Lammertsma, Bart N. M. van Berckel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2018-07-01
coleção:	EJNMMI Research
Assuntos:	PET NMDA Glutamate [18F]PK-209 Ketamine
Acesso em linha:	http://link.springer.com/article/10.1186/s13550-018-0424-2
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