Examining the Role of a Functional Deficiency of Iron in Lysosomal Storage Disorders with Translational Relevance to Alzheimer’s Disease

The recently presented Azalea Hypothesis for Alzheimer’s disease asserts that iron becomes sequestered, leading to a functional iron deficiency that contributes to neurodegeneration. Iron sequestration can occur by iron being bound to protein aggregates, such as amyloid β and tau, iron-rich structur...

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Hlavní autor:	Steven M. LeVine
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-11-01
Edice:	Cells
Témata:	Alzheimer’s disease Gaucher’s disease iron Krabbe’s disease lysosome mucolipidosis type IV
On-line přístup:	https://www.mdpi.com/2073-4409/12/22/2641
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