Mitochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer

Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared with European American (EA) patients, but the molecular mechanism underlying race-specific differences are unknown. To address this gap, we conducted comprehensive RNA-Seq, proteomics, and metabolomics analysis of B...

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Auteurs principaux:	Karthik Reddy Kami Reddy, Danthasinghe Waduge Badrajee Piyarathna, Jun Hyoung Park, Vasanta Putluri, Chandra Sekhar Amara, Abu Hena Mostafa Kamal, Jun Xu, Daniel Kraushaar, Shixia Huang, Sung Yun Jung, Livia S. Eberlin, Jabril R. Johnson, Rick A. Kittles, Leomar Y. Ballester, Krishna Parsawar, M. Minhaj Siddiqui, Jianjun Gao, Adriana Langer Gramer, Roni J. Bollag, Martha K. Terris, Yair Lotan, Chad J. Creighton, Seth P. Lerner, Arun Sreekumar, Benny Abraham Kaipparettu, Nagireddy Putluri
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical investigation 2024-09-01
Collection:	JCI Insight
Sujets:	Metabolism Oncology
Accès en ligne:	https://doi.org/10.1172/jci.insight.172336
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