Safety and Immunogenicity of a New Rotavirus-Inactivated Vaccine in the Chinese Adolescent Population: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial

Background: We performed a phase I experiment in a healthy teenage population in Sui County, Henan Province, China. The trial was randomized, double-blind, and placebo-controlled. Methods: Ninety-six adolescents were randomly assigned in three groups (high-dose, medium-dose, and low-dose) to receive...

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Bibliografische Detailangaben

Hauptverfasser:	Yan Liu, Guangwei Feng, Jinyuan Wu, Xinling Liu, Jing Pu, Yanxia Wang, Wangyang You, Na Yin, Shan Yi, Jiebing Tan, Xiaochen Lin, Lili Huang, Jiamei Gao, Qingchuan Yu, Qiumeng Tong, Yong Zhang, Rong Chen, Xiaoqing Hu, Jun Ye, Xiangjing Kuang, Yan Zhou, Zhongyu Hu, Dongyang Zhao, Hongjun Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-03-01
Schriftenreihe:	Vaccines
Schlagworte:	rotavirus-inactivated vaccine safety immunogenicity
Online-Zugang:	https://www.mdpi.com/2076-393X/13/4/369
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