Simultaneous enhancement of cellular and humoral immunity by the lymph node-targeted cholesterolized TLR7 agonist liposomes

Toll-like receptor (TLR) agonists, as promising adjuvants and immunotherapeutic agents, have the potential to enhance immune responses and modulate antigen-dependent T-cell immune memory through activation of distinct signaling pathways. However, their clinical application is hindered by uncontrolle...

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Hlavní autoři:	Dandan Wan, Ziyi Bai, Yu Zhang, Li Chen, Haiying Que, Tianxia Lan, Weiqi Hong, Jiayu Huang, Cai He, Yuquan Wei, Qiang Pu, Xiawei Wei
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-10-01
Edice:	Acta Pharmaceutica Sinica B
Témata:	TLR7 agonist Cationic liposomes Lymph node Cancer nanovaccines Immunotherapy Cross-presentation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211383524002375
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