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Clinical meaning of JAK2 V617F mutation in chronic myeloproliferative disorders – the first experience

<p>Background An acquired V617F mutation in the JAK2 gene was found to occur in most patients with polycythaemia vera (PV), and about a half of those with essential thrombocythaemia (ET) and chronic idiopathic myelofibrosis (CIMF). It is the first clonal marker that allows differentiation between re...

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Principais autores: Joško Vučković, Tadej Pajič, Rajko Kušec, Mateja Grat, Marjan Lorbek, Dinko Rogulj, Rok Pavlič, Ivan Žuran
Formato: Artigo
Idioma:Inglês
Publicado em: Slovenian Medical Association 2006-10-01
coleção:Zdravniški Vestnik
Assuntos:
chronic myeloproliferative disorders
essential thrombocythaemia
polycythaemia vera
idiophatic myelofibrosis
V617F mutation of JAK2
Acesso em linha:http://vestnik.szd.si/index.php/ZdravVest/article/view/2034
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