Low Expression of miR-466f-3p Sustains Epithelial to Mesenchymal Transition in Sonic Hedgehog Medulloblastoma Stem Cells Through Vegfa-Nrp2 Signaling Pathway

High-throughput analysis has improved the knowledge of medulloblastoma (MB), the leading cause of cancer related death in children, allowing a better comprehension of the key molecular pathways in MB pathogenesis. However, despite these advances, 30% of patients still die from the disease and surviv...

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Autori principali:	Zein Mersini Besharat, Claudia Sabato, Agnese Po, Francesca Gianno, Luana Abballe, Maddalena Napolitano, Evelina Miele, Felice Giangaspero, Alessandra Vacca, Giuseppina Catanzaro, Elisabetta Ferretti
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2018-11-01
Serie:	Frontiers in Pharmacology
Soggetti:	medulloblastoma sonic hedgehog medulloblastoma cancer stem cells epithelial to mesenchymal transition vegfa Nrp2 miR-466f-3p
Accesso online:	https://www.frontiersin.org/article/10.3389/fphar.2018.01281/full
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