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Targeting SLC6A8 suppresses tumor growth and enhances ferroptosis in hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) persists as a therapeutic challenge owing to restricted treatment alternatives and the dearth of effective biomarkers. The creatine transporter SLC6A8 has been documented to participate in the progression of various malignancies. However, the role t...

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Principais autores: Wenfang Bao, Yang Yu, Guofeng Yu, Jingde Chen, Yandong Li, Yanan Hai
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2026-03-01
Series:Journal of Cancer Research and Clinical Oncology
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Acceso en liña:https://doi.org/10.1007/s00432-026-06442-8
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