A Surrogate Animal Model for Screening of Ebola and Marburg Glycoprotein-Targeting Drugs Using Pseudotyped Vesicular Stomatitis Viruses

Filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV), cause severe hemorrhagic fever in humans and nonhuman primates with high mortality rates. There is no approved therapy against these deadly viruses. Antiviral drug development has been hampered by the requirement of a biosafety leve...

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Bibliografski detalji

Glavni autori:	Takeshi Saito, Junki Maruyama, Noriyo Nagata, Mao Isono, Kosuke Okuya, Yoshihiro Takadate, Yurie Kida, Hiroko Miyamoto, Akina Mori-Kajihara, Takanari Hattori, Wakako Furuyama, Shinya Ogawa, Shigeru Iida, Ayato Takada
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-08-01
Serija:	Viruses
Teme:	Filovirus Ebola virus Marburg virus recombinant vesicular stomatitis virus Syrian hamster animal model
Online pristup:	https://www.mdpi.com/1999-4915/12/9/923
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