A Novel Inducible Mouse Model of MLL-ENL-driven Mixed-lineage Acute Leukemia

Abstract. Previous retroviral and knock-in approaches to model human t(11;19)+ acute mixed-lineage leukemia in mice resulted in myeloproliferation and acute myeloid leukemia not fully recapitulating the human disease. The authors established a doxycycline (DOX)-inducible transgenic mouse model “iMLL...

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Principais autores:	Vaia Stavropoulou, Marwa Almosailleakh, Hélène Royo, Jean-François Spetz, Sabine Juge, Laurent Brault, Patrick Kopp, Michelina Iacovino, Michael Kyba, Alexandar Tzankov, Michael B. Stadler, Gianni Cazzaniga, Antoine H.F.M. Peters, Juerg Schwaller
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2018-08-01
Serija:	HemaSphere
Online dostop:	http://journals.lww.com/10.1097/HS9.0000000000000051
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