Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α

Hepatocyte nuclear factor 4α (HNF4α) regulates many genes that are preferentially expressed in liver. Mice lacking hepatic expression of HNF4α (HNF4αΔL) exhibited markedly increased levels of serum bile acids (BAs) compared with HNF4α-floxed (HNF4αF/F) mice. The expression of genes involved in the h...

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Bibliografiska uppgifter

Huvudupphov:	Yusuke Inoue, Ai-Ming Yu, Sun Hee Yim, Xiaochao Ma, Kristopher W. Krausz, Junko Inoue, Charlie C. Xiang, Michael J. Brownstein, Gösta Eggertsen, Ingemar Björkhem, Frank J. Gonzalez
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2006-01-01
Serie:	Journal of Lipid Research
Ämnen:	conditional knockout mice sterol 12α-hydroxylase oxysterol 7α-hydroxylase sterol carrier protein x cholic acid
Länkar:	http://www.sciencedirect.com/science/article/pii/S0022227520336701
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